Gene

mapk8a

ID
ZDB-GENE-080218-17
Name
mitogen-activated protein kinase 8a
Symbol
mapk8a Nomenclature History
Previous Names
  • jnk1a (1)
  • jnk1a-2 (1)
  • zgc:172209
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have JUN kinase activity. Predicted to be involved in JNK cascade and regulation of gene expression. Predicted to localize to cytoplasm and nucleus. Human ortholog(s) of this gene implicated in abdominal aortic aneurysm; benign rectal neoplasm; colorectal adenoma; and type 2 diabetes mellitus. Orthologous to human MAPK8 (mitogen-activated protein kinase 8).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mapk8a Human Ortholog
No data available
Associated With mapk8a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Conserved_site IPR003527 Mitogen-activated protein (MAP) kinase, conserved site
Domain IPR000719 Protein kinase domain
Family IPR008351 Mitogen-activated protein (MAP) kinase, JNK
Family IPR050117 Mitogen-activated protein kinase
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length Mitogen-activated protein kinase Mitogen-activated protein (MAP) kinase, conserved site Mitogen-activated protein (MAP) kinase, JNK Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:E9QBW8 427
UniProtKB:A0A8M6Z3T6 384
UniProtKB:A0A8M6Z2A6 421
UniProtKB:A8WG58 427
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA mapk8a-201 (1) Ensembl 1,618 nt
mRNA mapk8a-202 (1) Ensembl 2,211 nt
mRNA mapk8a-204 (1) Ensembl 1,796 nt
mRNA mapk8a-205 (1) Ensembl 421 nt
mRNA mapk8a-206 (1) Ensembl 2,254 nt
mRNA mapk8a-207 (1) Ensembl 2,254 nt
ncRNA mapk8a-003 (1) Ensembl 746 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations